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KMID : 0882420060700000335
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Korean Journal of Medicine
2006 Volume.70 No. 0 p.335 ~ p.340
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A case of NK/T-cell lymphoma in a cardiac transplant recipient
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Park Hye-Won
Byun Seung-Woon
Kim Jae-Joong
Song Meong-Gun
Han Eun-Mee
Huh Joo-Ryung
Suh Chul-Won
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Abstract
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Posttransplant lymphoproliferative disorder (PTLD) represent a potentially life-threatening complication following organ transplantation. The majority of PTLD are of B cell origin and strongly associated with Epstein-Barr Virus (EBV). PTLD of T cell origin are uncommon and have a poor prognosis. We encountered a case of NK/T-cell lymphoma involving posterior hypopharynx and appendix in a cardiac transplant recipient. The patient was a 67 year old woman who underwent cardiac transplantation in 1995. She was admitted in December 2004 after complaining of a sore throat for 2 weeks. The posterior hypopharyngeal mass was detected by laryngoscopic exam. On the 10th hospital day, fever and abdominal pain developed. Ultrasonography revealed acute appendicitis and appendectomy was performed. Excisional biopsy of posterior hypopharyngeal mass and appendectomy specimen showed nasal type NK/T-cell lymphoma, and it was assessed as PTLD. (Korean J Med 70:S335-S340, 2006)
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KEYWORD
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Lymphoproliferative disorder, Malignancy, Heart transplantation, Ebstein-Barr virus
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